## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation
Evidence of Nitrosative Damage in the Brain White Matter of Patients with Multiple Sclerosis
β Scribed by Oscar A. Bizzozero; Gisela DeJesus; Heather A. Bixler; Andrzej Pastuszyn
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 322 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
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## Abstract The purpose of this study is to define the topographical distribution of gray matter (GM) and white matter (WM) damage in patients with primary progressive multiple sclerosis (PPMS), using a multiparametric MRβbased approach. Using a 3 Tesla scanner, dualβecho, 3D fastβfield echo (FFE),