Evidence of linkage between the serotonin transporter and autistic disorder
โ Scribed by Jr, EH Cook; Courchesne, R; Lord, C; Cox, N J; Yan, S; Lincoln, A; Haas, R; Courchesne, E; Leventhal, B L
- Book ID
- 110058795
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 68 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1359-4184
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๐ SIMILAR VOLUMES
The serotonin transporter (5HTT) gene appears to be of particular interest as 5HTT is the selective site of action of selective serotonin reuptake inhibitors (SSRIs) that successfully treat bipolar depression (BP). The 5HTT gene is located on chromosome 17q11.1-q12 and has a 44 bp deletion/insertion
The present study was designed to assess linkage and linkage disequilibrium in two new ethnically distinct samples of families with primary autistic probands. The 5-HTT promoter repeat was genotyped in 54 singleton families collected in Italy and in 32 singleton and 5 multiplex families collected in