Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder
โ Scribed by Greenwood, Tiffany A. ;Alexander, Meghan ;Keck, Paul E. ;McElroy, Susan ;Sadovnick, A. Dessa ;Remick, Ronald A. ;Kelsoe, John R.
- Book ID
- 115548479
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 92 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0148-7299
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The serotonin transporter (5HTT) gene appears to be of particular interest as 5HTT is the selective site of action of selective serotonin reuptake inhibitors (SSRIs) that successfully treat bipolar depression (BP). The 5HTT gene is located on chromosome 17q11.1-q12 and has a 44 bp deletion/insertion