A critical step in the metastatic spread of tumour cells is the interaction of circulating tumour cells with the vascular endothelium. We have investigated the role of CD44 and its variants in the adhesion of a human melanoma cell line (RPMI-795 I) and a breast adenocarcinoma cell line (MDA-MB-23 I)
Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro
✍ Scribed by Véronique Trochon; Christelle Mabilat; Philippe Bertrand; Yves Legrand; Florence Smadja-Joffe; Claudine Soria; Bertrand Delpech; He Lu
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- French
- Weight
- 635 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The concept of the neurovascular unit emphasizes that common signals and substrates underlie the physiology and pathophysiology of neuronal and endothelial compartments in brain. Recent data suggest that activation of the integrin‐associated protein CD47 promotes neuronal cell death. Is
## Abstract In recent studies, we have shown that baicalein and baicalin, 2 major flavonoids of __Scutellaria baicalensis__ Georgi, exhibit anticancer activity against several cancers __in vitro__. In our present study, we assessed their potential as anti‐angiogenic agents __in vivo__ employing chi
Osteopontin (OPN) is a secreted glycoprotein with mineral-and cell-binding properties that can regulate cell activities through integrin receptors. Previously, we identified an intracellular form of osteopontin with a perimembranous distribution in migrating fetal fibroblasts (Zohar et al., J Cell P
Neovascularization in the adult central nervous system occurs as a response to several pathophysiological conditions such as ischemia, wound repair, or neoplasia. Endothelial cells from different blood vessel types, different organs, and different species are heterogeneous; therefore, the appropriat