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Evidence of chromosomal inversion using fluorescence in situ hybridization to stretched DNA

โœ Scribed by Florence Salomon-Nguyen; Maryvonne Le Coniat-Busson; Roland Heilig; Dominique Campion; Jean Weissenbach; Roland Berger


Book ID
117578367
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
481 KB
Volume
321
Category
Article
ISSN
0764-4469

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In situ hybridization of hamsterlhuman hybrids with biotinylated human genomic D N A has revealed that human chromosomal DNA can integrate into the hamster genome and is not always cytologically detectable. This finding helps t o explain why discordancy can arise in gene mapping by failing to recogn