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Evidence of altered TrkB pre-mRNA splicing in Alzheimer's disease

✍ Scribed by Wong, Jenny; Garner, Brett; Halliday, Glenda; Kwok, John


Book ID
123110826
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
204 KB
Volume
8
Category
Article
ISSN
1552-5260

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## Abstract Recent genomewide analyses of alternative splicing (AS) indicate that up to 70% of human genes may have alternative splice forms, suggesting that AS together with various posttranslational modifications plays a major role in the production of proteome complexity. Splice‐site selection u