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Evidence of 5-lipoxygenase overexpression in the skin of patients with systemic sclerosis: A newly identified pathway to skin inflammation in systemic sclerosis

✍ Scribed by Otylia Kowal-Bielecka; Oliver Distler; Michel Neidhart; Peter Künzler; Janine Rethage; Michael Nawrath; Anna Carossino; Thomas Pap; Ulf Müller-Ladner; Beat A. Michel; Stanislaw Sierakowski; Marco Matucci-Cerinic; Renate E. Gay; Steffen Gay


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
921 KB
Volume
44
Category
Article
ISSN
0004-3591

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✍ Charles W. Denko; Richard B. Stoughton 📂 Article 📅 1958 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB 👁 2 views

## Abstract A preliminary study of the fate of radioactive sulfur (Na~2~S^35^O~4~) given intravenously to patients with progressive systemic sclerosis has revealed an appreciably greater radioactivity in the involved skin. The evidence presented suggests an abnormal rate of uptake of sulfur in the