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Evidence in Rat and Mouse Liver for Temporal Control of Two Forms of Cytochrome P-450 Inducible by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

✍ Scribed by Thomas M. GUENTHNER; Daniel W. NEBERT


Book ID
115116940
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
858 KB
Volume
91
Category
Article
ISSN
1432-1327

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2,3,7,8-Tetrachlorodibenzo-p-dioxin indu
✍ Stefanie Knerr; Johanna Schaefer; Saskia Both; Angela Mally; Wolfgang Dekant; Di πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 610 KB

## Abstract 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) was classified by the International Agency for Research on Cancer as a carcinogen in humans. It acts through an aryl hydrocarbon receptor‐mediated mechanism, inducing the transcription of numerous genes, including various cytochrome P450s (CYPs