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2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced changes in the hydroxylation of biphenyl by rat liver microsomes

✍ Scribed by Gary E.R. Hook; Terry C. Orton; John A. Moore; George W. Lucier


Book ID
115772587
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
745 KB
Volume
24
Category
Article
ISSN
0006-2952

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## Abstract The administration of single oral doses of 200 ΞΌg kg^βˆ’1^ of 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin to females of the outbred, Lac: P strain of rat results in the formation of hepatic multinucleate cells by cell fusion. Liver cell plasma membranes isolated 6 or 11 days after dosing show