Evidence for Transcriptional Activity in the Syncytiotrophoblast of the Human Placenta
โ Scribed by P.M. Ellery; T. Cindrova-Davies; E. Jauniaux; A.C. Ferguson-Smith; G.J. Burton
- Book ID
- 113854439
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 550 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0143-4004
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The syncytiotrophoblastic brush border of the human placenta forms the maternalfetal interface and is an important determinant of placental function. Electron micrographs of fresh brush border preparations isolated from first-trimester human placentas showed membrane vesicles, open-ended microvilli,
## An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta During normal human pregnancy, maternal IgG crosses the placenta and provides passive immunity for the fetus. In so doing, IgG passes through two cellular barriers: the syncytiotrophoblast and the fetal capil