An effective method for the synthesis of
An effective method for the synthesis of the cap structure of eukaryotic messenger ribonucleic acids
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Takashi Kamimura; Yumi Osaki; Mitsuo Sekine; Tsujiaki Hata
📂
Article
📅
1984
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Elsevier Science
🌐
French
⚖ 259 KB
A new promising "capping agent" (x) was synthesized by use of a lipophilic amino protecting group and an activatable pyrophosphate protecting group. This agent reacted homogeneously with 5;rnucleotides in the presence of AgN03 to afford the cap structures (m7G pppNu).