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An effective method for the synthesis of the cap structure of eukaryotic messenger ribonucleic acids

✍ Scribed by Takashi Kamimura; Yumi Osaki; Mitsuo Sekine; Tsujiaki Hata


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
259 KB
Volume
25
Category
Article
ISSN
0040-4039

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✦ Synopsis


A new promising "capping agent" (x) was synthesized by use of a lipophilic amino protecting group and an activatable pyrophosphate protecting group.

This agent reacted homogeneously with 5;rnucleotides in the presence of AgN03 to afford the cap structures (m7G pppNu).


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