## Abstract α‐Fluorocarboxamides 3a–3e can be prepared by treatment of the corresponding α‐hydroxycarboxamides with diethylaminosulfur trifluoride. The infrared spectra argue strongly against the existence of intramolecular hydrogen bonds between the amino group and the fluorine atom.
Evidence for strong intramolecular hydrogen bonding in some quinoline derivatives
✍ Scribed by Marzia Ballbio; Stefano Del Nero; Aristide Vigevani
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 163 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0749-1581
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Several analogues of quinoline‐8‐carboxamide were examined by ^1^H NMR and IR in order to establish structural requirements for strong intramolecular hydrogen bonding.
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