Evidence for adaptive selection acting o
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Eduardo Ruiz-Pesini; Douglas C. Wallace
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Article
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2006
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John Wiley and Sons
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English
β 547 KB
In order to identify putative adaptive human mitochondrial DNA (mtDNA), transfer RNA (tRNA), and ribosomal RNA (rRNA) variants, we assembled a sequential mutational tree from 2,460 human mtDNA coding sequences, thus providing the relative age of all mtDNA sequence variants. Deleterious mutations aff