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Evidence for male X chromosomal mosaicism in X-linked agammaglobulinemia

✍ Scribed by R. W. Hendriks; E. J. B. M. Mensink; M. E. M. Kraakman; A. Thompson; R. K. B. Schuurman


Publisher
Springer
Year
1989
Tongue
English
Weight
555 KB
Volume
83
Category
Article
ISSN
0340-6717

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Father-to-daughter transmission of focal
✍ Gorski, Jerome L. πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 696 KB

tern of X-inactivation; 11 of 11 hybrids contained an active maternal X chromosome (x2 = 12.2, P = .001). These findings indicated that, in this family, FDH was associated with a nonrandom pattern of X-inactivation consistent with X-linked inheritance, suggesting that the patient's father was mosaic