✦ LIBER ✦
Father-to-daughter transmission of focal dermal hypoplasia associated with nonrandom X-inactivation: Support for X-linked inheritance and paternal X chromosome mosaicism
✍ Scribed by Gorski, Jerome L.
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 696 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
✦ Synopsis
tern of X-inactivation; 11 of 11 hybrids contained an active maternal X chromosome (x2 = 12.2, P = .001). These findings indicated that, in this family, FDH was associated with a nonrandom pattern of X-inactivation consistent with X-linked inheritance, suggesting that the patient's father was mosaic for a mutant FDH allele.