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Evidence for an alternative pathway of xanthine oxidation in Aspergillus nidulans

✍ Scribed by A.J. Darlington; C. Scazzocchio


Book ID
115743111
Publisher
Elsevier Science
Year
1968
Weight
175 KB
Volume
166
Category
Article
ISSN
0005-2787

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πŸ“œ SIMILAR VOLUMES


A mutation defective in the xanthine alt
✍ Sealy-Lewis, Heather M. ;Scazzocchio, Claudio ;Lee, Sidney πŸ“‚ Article πŸ“… 1978 πŸ› Springer 🌐 English βš– 560 KB

In Aspergillus nidulans uric acid can be produced from xanthine via purine hydroxylase I (xanthine dehydrogenase) or via the xanthine alternative pathway (Darlington and Scazzocchio, Biochem. Biophys. Acta, 166, 569--571; 1968). A mutation defective in the xanthine alternative pathway of Aspergillus

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Three unlinked genes where mutation can lead to D(+)-pantothenic acid auxotrophy in Aspergillus nidulans have been identified. pantoA is probably the structural gene for pantothenate synthetase (EC 6.3.2.1) whilst pantoB and pantoC are involved in the syntheses of D-pantoic acid and beta-alanine, re