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Evidence for altered catalytic properties of the cytochrome P-450 involved in sparteine oxidation in poor metabolizers

✍ Scribed by Osikowska-Evers, B; Dayer, P; Meyer, U A; Robertz, G M; Eichelbaum, M


Book ID
109844241
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
332 KB
Volume
41
Category
Article
ISSN
0009-9236

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Peroxidase activity was partially purified from neonatal (3 to 6 days old) rat skin. The membrane-bound peroxidase activity was extracted with 0.5 M calcium chloride and was monitored spectrophotometrically at 470 nm with 2-methoxyphenol (guaiacol) and hydrogen peroxide as substrates. Subcellular di