In vitro studies were carried out to identify the major contribution of CYP2C8, CYP2D6 and CYP3A4 to the metabolism of perospirone (cis-N-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]cyclohexane-1,2-dicarboximide monohydrochloride dehydrate), a novel antipsychotic agent, using human liver mic
In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine
β Scribed by Jiang Ping Luo; Sarvesh C. Vashishtha; Edward M. Hawes; Gordon McKay; Kamal K. Midha; Jim Fang
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 220 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0142-2782
- DOI
- 10.1002/bdd.768
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