## Abstract The receptor for advanced glycation endproducts (RAGE) has a well‐substantiated role in cell dysfunction and mechanisms of inflammatory disease. The physiological agonists of RAGE are less certain: S100/calgranulin proteins, high mobility group‐1 protein HMGB1 and other proteins are can
Evidence against dietary advanced glycation endproducts being a risk to human health
✍ Scribed by Jennifer M. Ames
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 393 KB
- Volume
- 51
- Category
- Article
- ISSN
- 1613-4125
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
In vivo, advanced glycation endproducts (AGEs) are linked to various diseases, particularly those associated with diabetes. AGEs are also formed when many foods are thermally processed. The extent to which dietary AGEs are absorbed by the gastrointestinal (GI) tract and their possible role in the onset and promotion of disease are currently of considerable interest. This paper reviews information that supports the argument that dietary AGEs are not a risk to human health.
Introduction: http://dx.doi.org/10.1002/mnfr.200700067
Pro arguments: http://dx.doi.org/10.1002/mnfr.200700035
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## Abstract We are interested in the regulation of intracellular calcium and the various diseases associated with an altered regulation of this second messenger. More recently, we also became interested in pathologies involving the Ca2+‐binding S100 proteins and AGEs and their association with the