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Evasion of Toll-like receptor 2 activation by staphylococcal superantigen-like protein 3

✍ Scribed by Bardoel, B. W.; Vos, R.; Bouman, T.; Aerts, P. C.; Bestebroer, J.; Huizinga, E. G.; Brondijk, T. H. C.; Strijp, J. A. G.; Haas, C. J. C.

Book ID: 118778755
Publisher: Springer
Year: 2012
Tongue: English
Weight: 534 KB
Volume: 90
Category: Article
ISSN: 0946-2716
DOI: 10.1007/s00109-012-0926-8

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## Location Matters Plasmacytoid dendritic cells (pDCs), an immune cell specialized to respond to viral infections, use Toll-like receptors (TLRs) 7 and 9 expressed in endosomes to sense viral nucleic acids. Triggering of TLR7 or 9 results in the induction of two distinct signaling pathways, one th