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Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

✍ Scribed by Sasai, Miwa (author);Linehan, Melissa M. (author);Iwasaki, Akiko (author)

Book ID
127302776
Publisher
American Association for the Advancement of Science
Year
2010
Tongue
English
Weight
956 KB
Volume
329
Category
Article
ISSN
0036-8075

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Bifurcation of Toll-Like Receptor 9 Sign
Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3
✍ Sasai, Miwa (author);Linehan, Melissa M. (author);Iwasaki, Akiko (author) πŸ“‚ Article πŸ“… 2010 πŸ› American Association for the Advancement of Scienc 🌐 English βš– 956 KB

## Location Matters Plasmacytoid dendritic cells (pDCs), an immune cell specialized to respond to viral infections, use Toll-like receptors (TLRs) 7 and 9 expressed in endosomes to sense viral nucleic acids. Triggering of TLR7 or 9 results in the induction of two distinct signaling pathways, one th