Evaluation of unnatural cyclic amino acids as boron delivery agents for treatment of melanomas and gliomas
β Scribed by Barth, Rolf F.; Kabalka, George W.; Yang, Weilian; Huo, Tianyao; Nakkula, Robin J.; Shaikh, Aarif L.; Haider, Syed A.; Chandra, Subhash
- Book ID
- 122180389
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 434 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0969-8043
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## Abstract We have synthesized __N__βFmoc amino acid derivatives bearing boronated and carboranylated substituents. Thus, a 1,3,2βdioxaborolane subunit has been introduced on the side chain of __N__^Ξ±^βFmocβLβlysine, and a bis(carboranylated) Ξ³βamino acid building block has been prepared. As shown