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Evaluation of “True” Creatinine Clearance in Rats Reveals Extensive Renal Secretion

✍ Scribed by Inger M. Darling; Marilyn E. Morris


Book ID
110341450
Publisher
Springer US
Year
1991
Tongue
English
Weight
1024 KB
Volume
08
Category
Article
ISSN
0724-8741

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From the determination of the Michaehs-Menten kinetic parameters (V, and Km) of renal tubular secretion of D-( -)p-n-propylmandelic acid (V) and D-( -)-p-isopropylmandelic acid (VI) in rats, it is shown that these compounds involve the same renal tubular carrier for their secretion but the affinity