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Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy

✍ Scribed by Sebahattin Vurucu; Erkan Demirkaya; Mustafa Kul; Bulent Unay; Davut Gul; Rıdvan Akin; Erdal Gokçay


Book ID
116841244
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
152 KB
Volume
32
Category
Article
ISSN
0278-5846

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## Abstract ## Background Poor glycaemic control, hypertension and duration of diabetes are risk factors for the development of diabetic nephropathy, but there may be genetic factors. Recently, a common C to T mutation at nucleotide position 677 of the MTHFR gene (MTHFR677C > T) has been reported