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Evaluation of the nuclear DNA Diffusion Assay to detect apoptosis and necrosis

✍ Scribed by Tomáš Gichner; Anita Mukherjee; Elizabeth D. Wagner; Michael J. Plewa

Book ID
116758999
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
490 KB
Volume
586
Category
Article
ISSN
1383-5718

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Detection of DNA fragments in situ using the terminal deoxyribonucleotidyl transferase (TDTbmediated dUTP-digoxigenin nick end labeling (TUNEL) assay is increasingly applied to investigate active cell death (apoptosis). We studied the specificity of the assay i n well-defined models of apoptosis and