By use of rat cDNA probes and a panel of cell hybrids segregating rat chromosomes, the genes encoding three pyridoxal 5'-phosphate (PLP)-dependent decarboxylases--namely, DOPA-decarboxylase (Ddc), glutamic acid decarboxylase 1 and 2 (Gad1 and Gad2)--were assigned to rat Chromosomes (Chrs) 14, 3, and
✦ LIBER ✦
Evaluation of the glutamate decarboxylase genes Gad1 and Gad2 as candidate genes for acute ethanol withdrawal severity in mice
✍ Scribed by Christoph Fehr; Brooks L.S Rademacher; Kari J Buck
- Book ID
- 117449110
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 233 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0278-5846
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It is widely believed that expression of the vesicular glutamate transporter genes VGLUT1 and VGLUT2 is restricted to glutamatergic neurons and that the two transporters segregate in different sets of neurons. Using single-cell multiplex RT-PCR (sc-RT-mPCR), we show that VGLUT1 and VGLUT2 mRNAs were