## Abstract The mutagenic potential of zinc pyrithione (Znpt) was evaluated __in vitro__ in the __Salmonella__/mammalian microsome plate incorporation mutagenicity (Ames) assay and the CHO/HGPRT gene mutation assay. The clastogenic potential of Znpt was evaluated __in vivo__ using the mouse micronu
β¦ LIBER β¦
Evaluation of the genotoxic potential of some microbial volatile organic compounds (MVOC) with the comet assay, the micronucleus assay and the HPRT gene mutation assay
β Scribed by Ludwika Kreja; Hans-Joachim Seidel
- Book ID
- 117766847
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 80 KB
- Volume
- 513
- Category
- Article
- ISSN
- 1383-5718
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Paclitaxel is a recent chemotherapeutic agent that inhibits tubulin depolymerization in tumoral cells. Despite its increasing use against various human cancers, the genotoxicity of paclitaxel has never been studied on normal human cells. The in vitro genotoxic effects of the drug were evaluated with