✦ LIBER ✦

Evaluation of the effect of syringe surfaces on protein formulations

✍ Scribed by Sumit Majumdar; Brandi M. Ford; Kevin D. Mar; Vince J. Sullivan; Robert G. Ulrich; Ajit Joseph M. D'souza

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 902 KB
Volume: 100
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.22515

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

An effective method for quantitative eva

An effective method for quantitative evaluation of proteins adsorbed on biomaterial surfaces

✍ X. Y. Lü; Y. Huang; W. P. Qian; Z. M. Tang; Z. H. Lu 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 230 KB

An effective method for the quantitative evaluation of proteins adsorbed on biomaterial surfaces has been developed. First, the kinetic behavior of a range of human fibrinogen (Fib) adsorbed onto polystyrene (PS) films was investigated by using a reflectometry interference spectroscopy setup. The sp

Adsorption of a Formulated Protein on a

Adsorption of a Formulated Protein on a Drug Delivery Device Surface

✍ Stelios T. Tzannis; William J.M. Hrushesky; Patricia A. Wood; Todd M. Przybycien 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 244 KB

## Protein-surface interaction phenomena have been studied The interactions between therapeutic proteins and delivery deextensively during the past 15 years (1, 2). However, much vice surfaces may have a significant impact on the efficacy of a of this work has been focused on the adsorption of pla

The effects of surface adsorption on the

The effects of surface adsorption on the thermal stability of proteins

✍ Bryan L. Steadman; Karen C. Thompson; C. Russell Middaugh; Ken Matsuno; Susan Vr 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 841 KB

Evaluation of the effect of ammonium car

Evaluation of the effect of ammonium carbamate on the stability of proteins

✍ Lucimara Lopes da Silva; Pedro de Alcântara Pessôa Filho; Everson Alves Miranda 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 99 KB

## Abstract **BACKGROUND:** The use of the volatile salt ammonium carbamate in protein downstream processing has recently been proposed. The main advantage of using volatile salts is that they can be removed from precipitates and liquid effluents through pressure reduction or temperature increase.

A numerical study on the effective dimen

A numerical study on the effective dimension of protein surfaces

✍ L Fernández Pacios 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 515 KB

The geometrical complexity of proteins is studied in terms of the effective dimension D associated with the solvent contact molecular surface. The apparent dispersion of values proposed in recent years for fractal dimensions in proteins is studied and an explanation proposed. The contribution of the

The effect of sucrose hydrolysis on the

The effect of sucrose hydrolysis on the stability of protein therapeutics during accelerated formulation studies

✍ Douglas D. Banks; David M. Hambly; Joanna L. Scavezze; Christine C. Siska; Nicol 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 185 KB 👁 1 views

Stability studies of protein therapeutics are often accelerated by storing potential formulations at elevated temperatures where the rates of various chemical and physical degradation pathways are increased. An often overlooked caveat of using these studies is the potential degradation of the formul