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Evaluation of the effect of hypoxia on the expression and activity of neprilysin (EC 3.4.24.11), a protease involved on Alzheimer’s disease

✍ Scribed by Watanabe De Oliveira, R.; Silva Julian, G.; Cini Perry, J.; Tufik, S.; Visniauskas, B.; Ribeiro Chagas, J.


Book ID
122270002
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
39 KB
Volume
14
Category
Article
ISSN
1389-9457

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Iron is essential for many biological processes, including oxygen delivery, and its supply is tightly regulated. Iron regulatory proteins (IRPs, IRP1 and IRP2) are master regulators of cellular iron metabolism. Hypoxia triggers a broad range of gene responses that are primarily mediated by hypoxia-i