Background. Cytogenetic studies, framed to assess the possible genomic damage caused by areca nut consumption (without tobacco and not as a component of betel quid), were performed among areca nut chewers, which included normal people who chew areca nuts, patients with oral submucous fibrosis, and p
Evaluation of the carcinogenicity of different preparations of areca nut in mice
โ Scribed by A. Ramesha Rao; Padma Das
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 527 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
โฆ Synopsis
A r e a nut has been used as a masticatory since antiquity and it is estimated that more than 10% of the world population chews it in a variety of forms. We have evaluated the carcinogenicity of different preparations of areca nut: ripeunprocessed-sundried nut (R-UP-SD), ripe-processedsundried nut (R-P-SD), unripe-processed-sundried nut (UR-P-SD). ripe-unprocessed-sundried-water-soaked nut (R-UP-SD-WS) and ripe-unprocessed-undried-water-soaked nut (R-UP-UD-WS) in mice following diet-feeding or oral feeding for I 2 months. Only unprocessed areca nuts (R-UP-SD. R-UP-SD-WS and R-UP-UD-WS), at high doses, displayed a very weak carcinogenicity.
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