𝔖 Bobbio Scriptorium
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Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811

✍ Scribed by Kaku Goto; Koichi Watashi; Takayuki Murata; Takayuki Hishiki; Makoto Hijikata; Kunitada Shimotohno


Book ID
116292610
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
580 KB
Volume
343
Category
Article
ISSN
0006-291X

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The cyclophilin inhibitor Debio-025 show
✍ Robert Flisiak; Andrzej Horban; Philippe Gallay; Michael Bobardt; Suganya Selvar πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 522 KB

Debio-025 is an oral cyclophilin (Cyp) inhibitor with potent anti-hepatitis C virus activity in vitro. Its effect on viral load as well as its influence on intracellular Cyp levels was investigated in a randomized, double-blind, placebo-controlled study. Mean hepatitis C viral load decreased signifi