Preparation of budesonide/γ-cyclodextrin
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Tarja Toropainen; Sitaram Velaga; Teemu Heikkilä; Laura Matilainen; Pekka Jarho;
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Article
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2006
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John Wiley and Sons
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English
⚖ 314 KB
The aim was to investigate if solid drug/cyclodextrin complexes could be produced in a single-step process with a solution enhanced dispersion by supercritical fluids (SEDS) method. Budesonide and gamma-cyclodextrin (CD) solutions (50% or 99.5% ethanol) were pumped from the same (conventional method