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Evaluation of supercritical fluid technology as preparative technique of benzocaine–cyclodextrin complexes—Comparison with conventional methods

✍ Scribed by Ali H. Al-Marzouqi; Baboucarr Jobe; Ali Dowaidar; Francesca Maestrelli; Paola Mura


Book ID
108189323
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
882 KB
Volume
43
Category
Article
ISSN
0731-7085

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The aim was to investigate if solid drug/cyclodextrin complexes could be produced in a single-step process with a solution enhanced dispersion by supercritical fluids (SEDS) method. Budesonide and gamma-cyclodextrin (CD) solutions (50% or 99.5% ethanol) were pumped from the same (conventional method