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Evaluation of Structural and Evolutionary Contributions to Deleterious Mutation Prediction

✍ Scribed by Christopher T Saunders; David Baker


Book ID
117143002
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
484 KB
Volume
322
Category
Article
ISSN
0022-2836

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As more studies are turning to bioinformatic prediction programs to assess the potential impact of amino acid substitutions, it is relevant to evaluate the prediction results these programs give in genes that have been well-characterized for Mendelian diseases. Eight genes responsible for neurodegen