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Evaluation of spontaneous and chemical-induced lacI mutations in germ cells from lambda/lacI transgenic mice

✍ Scribed by Donald L Putman; A Penn Ritter; Gregory J Carr; Robert R Young


Book ID
117767371
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
165 KB
Volume
388
Category
Article
ISSN
1383-5718

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The advent of transgenic technology has greatly fa-deamination-directed mutation at methylated cytocilitated the study of mutation in animals in vivo. sine bases. The second most common class of muta-The Big Blue mouse system, transgenic for the lacI tions is G:C r T:A transversions. A significant c