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Evaluation of local cerebral glucose utilization and the permeability of the blood-brain barrier in the genetically epilepsy-prone rat

✍ Scribed by A. Saija; P. Princi; R. De Pasquale; G. Costa; G. B. De Sarro


Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
968 KB
Volume
88
Category
Article
ISSN
0014-4819

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✍ James W. Critchfield; G.Frank Carl; Carl L. Keen πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 825 KB

Human and experimental animal studies suggest a relationship between low Mn status and seizures. The genetically epilepsy prone rat (GEPR), which has low tissue Mn levels, was studied in the context of Mn supplementation. Manganese was provided at 45 pg/g diet (control) or 1000 pg/g diet (supplement