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Evaluation of female intrapelvic tumors by clinical proton MR spectroscopy

✍ Scribed by Toshiko Okada; Masafumi Harada; Kenji Matsuzaki; Hiromu Nishitani; Toshihiro Aono

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
275 KB
Volume
13
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

We measured metabolites in large tumors of the female pelvis (23 cases total: 6 malignant cases, 17 benign cases) using single‐voxel proton magnetic resonance (MR) spectroscopy and evaluated the clinical significance of this method in the differential diagnosis of female pelvic tumors. The characteristically obtained signal was lactate, which was detected not only in all the malignant tumors but also in some of the benign tumors. However, the lactate signals of the malignant tumors tended to form higher peaks than those of benign tumors, which was a finding consistent with the result of the earlier in vitro study reported in ovarian tumors. The signal of choline‐containing compounds (Cho) was found only in solid tumors, and the signal intensity varied among different histological types of tumors, possibly reflecting metabolic activity of the cell membrane. We considered that proton MR spectroscopy (MRS) of intrapelvic tumors would be useful for the diagnosis of the nature of female intrapelvic tumors. J. Magn. Reson. Imaging 2001;13:912–917. © 2001 Wiley‐Liss, Inc.

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