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Evaluation of enantioselective binding of antihistamines to human serum albumin by ACE

✍ Scribed by María Amparo Martínez-Gómez; Rosa M. Villanueva-Camañas; Salvador Sagrado; María José Medina-Hernández

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
304 KB
Volume
28
Category
Article
ISSN
0173-0835

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Evaluation of enantioselective binding of fluoxetine to human serum albumin by ultrafiltration and CE – Experimental design and quality considerations
✍ Lucía Asensi-Bernardi; Yolanda Martin-Biosca; Rosa María Villanueva-Camañas; Mar 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 292 KB 👁 1 views

## Abstract Several pharmacokinetic processes are affected by enantioselectivity (ES). At the level of distribution, protein binding (PB) is one of the most important. The enantioselective binding of fluoxetine (FLX) to HSA has been evaluated in this work by ultrafiltration of FLX–HSA mixtures and