Mitochondria as the target for mildronat
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Jolanta Pupure; Maria A. S. Fernandes; Maria S. Santos; António J. M. Moreno; Iv
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Article
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2008
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John Wiley and Sons
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English
⚖ 255 KB
👁 2 views
## Abstract Previously mildronate, an aza‐butyrobetaine derivative, was shown to be a cytoprotective drug, through its mechanism of action of inhibition of carnitine palmitoyltransferase‐1, thus protecting mitochondria from long‐chain fatty acid accumulation and subsequent damage. Recently in an az