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Evaluation of cytotoxicity of surfactants used in self-micro emulsifying drug delivery systems and their effects on paracellular transport in Caco-2 cell monolayer

✍ Scribed by Zoltán Ujhelyi; Ferenc Fenyvesi; Judit Váradi; Pálma Fehér; Tímea Kiss; Szilvia Veszelka; Mária Deli; Miklós Vecsernyés; Ildikó Bácskay

Book ID: 116438692
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 936 KB
Volume: 47
Category: Article
ISSN: 0928-0987
DOI: 10.1016/j.ejps.2012.07.005

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## Abstract Poly[methacrylic acid‐grafted‐poly(ethylene glycol)] [P(MAA‐__g__‐EG)] is a complexation hydrogel molecularly designed for oral peptide delivery. In this work, the cytotoxicity and insulin‐transport enhancing effect of P(MAA‐__g__‐EG) microparticles on intestinal epithelial cells were e