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Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects

✍ Scribed by Faith Pangilinan, Anne M Molloy, James L Mills, James F Troendle, Anne Parle-McDermott, Caroline Signore, Valerie B O’Leary, Peter Chines, Jessica M Seay, Kerry Geiler-Samerotte, Adam Mitchell, Julia E VanderMeer, Kristine M Krebs, Angelica Sanchez, Joshua Cornman-Homonoff, et al


Book ID
119896647
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
447 KB
Volume
13
Category
Article
ISSN
1471-2350

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## Background: Decreased maternal folate levels are associated with having a child with a neural tube defect (ntd), and periconceptual folic acid supplementation reduces this risk by >50%. vitamin b(12) (as methylcobalamin) is a cofactor for methionine synthase, an enzyme that plays a key role in f