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Evaluation of folate metabolism gene polymorphisms as risk factors for open and closed neural tube defects

✍ Scribed by K. Doudney; J. Grinham; J. Whittaker; S.A. Lynch; D. Thompson; G.E. Moore; A.J. Copp; N.D.E. Greene; P. Stanier


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
75 KB
Volume
149A
Category
Article
ISSN
1552-4825

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## Background: Decreased maternal folate levels are associated with having a child with a neural tube defect (ntd), and periconceptual folic acid supplementation reduces this risk by >50%. vitamin b(12) (as methylcobalamin) is a cofactor for methionine synthase, an enzyme that plays a key role in f

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