𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Evaluation of Cellular Responses to Rotavirus and NSP4 in Children during Natural Rotavirus Infection

✍ Scribed by Jyoti Logani; Santosh Gupta; Shinjini Bhatnagar; Pratima Ray; M.K. Bhan


Book ID
113539775
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
58 KB
Volume
123
Category
Article
ISSN
1090-2341

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Non-structural protein NSP2 induces hete
✍ Carl D. Kirkwood; Karen Boniface; Simone Richardson; Zenobia F. Taraporewala; Jo πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 260 KB

## Abstract Rotaviruses are the single most important causes of severe acute diarrhoea in children worldwide. Despite success in developing vaccines, there is still a lack of knowledge about many components of the immune response, particularly those to non‐structural proteins. This study establishe

Humoral and cell-mediated immune respons
✍ Johansen, Kari; Hinkula, Jorma; Espinoza, Felix; Levi, Mikael; Zeng, Carl; RudοΏ½n πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 122 KB πŸ‘ 2 views

Rotavirus nonstructural protein NSP4 has recently been suggested to function as a viral enterotoxin and play a role in the pathophysiological mechanism whereby rotaviruses induce diarrhea. The ability of rotavirus NSP4 to stimulate a humoral immune response was examined in naturally infected childre

Systemic and intestinal antibody respons
✍ Cristiana Iosef; Kyeong-Ok Chang; Marli S.P. Azevedo; Linda J. Saif πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 148 KB

Antibody responses to the Wa human rotavirus (HRV) nonstructural protein NSP4, a viral enterotoxin, were evaluated in neonatal gnotobiotic (Gn) pigs. Gn pigs were inoculated orally with one dose of 10(5) fluorescent focus units (FFU) of virulent Wa HRV (HRV-V), to mimic natural infection, or with th

Serologic responses by immunoblot follow
✍ Begue, Rodolfo E.; Martin, Paula; Dennehy, Penelope H. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 138 KB

Serologic responses to proteins of rotavirus serotypes G1, P1A[8]; G2, P1B [4]; G3, P1A[8]; and G4, P2A[6] were evaluated by immunoblotting paired sera from 17 children with primary rotavirus infection. Ten children were infected with G1, P1A[8]; five with G4, P1A[8]; and two with G4, P2A[6] viruses

Homotypic and heterotypic serum neutrali
✍ Gorrell, Rebecca J.; Bishop, Ruth F. πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 149 KB

Worldwide trials of rotavirus vaccines are currently in progress, but the basis of cross-reactive immunity between rotavirus serotypes is yet to be elucidated. The involvement of the outer capsid proteins, VP7 and VP4, in the production of cross-reactive neutralizing antibody (N-Ab) is unclear, and