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Evaluation of blood-brain barrier (BBB) permeability during MDP-inducing fever

✍ Scribed by G. Riveau; P. Lacombe; L. Chedid; J. Seylaz

Book ID
103624458
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
94 KB
Volume
7
Category
Article
ISSN
0192-0561

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Permeability data from MDR1-MDCKII and PAMPA-BBB assays were compared to data from in situ brain perfusion to evaluate the accuracy of in vitro assays in predicting in vivo blood-brain barrier (BBB) permeability. PAMPA-BBB significantly correlated to in situ brain perfusion, however, MDR1-MDCKII had