## Abstract Binding interactions of a new series of anthrapyrazoles (APs) with DNA were evaluated by electrospray ionization mass spectrometry (ESIβMS). Relative binding affinities were estimated from the ESIβMS data based on the fraction of bound DNA for DNA/anthrapyrazole mixtures, and they show
Evaluation of Binding of Perylene Diimide and Benzannulated Perylene Diimide Ligands to DNA by Electrospray Ionization Mass Spectrometry
β Scribed by Carolyn L. Mazzitelli; Jennifer S. Brodbelt; Jonathan T. Kern; Mireya Rodriguez; Sean M. Kerwin
- Book ID
- 108158308
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 390 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1044-0305
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The relative nonβcovalent binding behavior of two small molecule ligands to the tetrameric protein streptavidin was investigated by electrospray ionization mass spectrometry (ESIβMS). An extended __m__/__z__ range quadrupole mass spectrometer was employed to observe the intact multimeri
## Abstract We describe an approach for the determination of binding constants for proteinβligand complexes with electrospray ionization mass spectrometry, based on the observation of unbound ligands competing for binding to a protein target. For the first time, dissociation constants lower than pi