Evaluation of Antioxidative Constituents from Thyme

✍ Scribed by Schwarz, Karin; Ernst, Hedda; Ternes, Waldemar

• Book ID: 102647649
• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 592 KB
• Volume: 70
• Category: Article
• ISSN: 0022-5142
• DOI: 10.1002/(sici)1097-0010(199602)70:2<217::aid-jsfa488>3.0.co;2-y

✦ Synopsis

The non-polar fraction of thyme was examined for the occurrence of phenolic components and their antioxidative activity. In addition to carvacrol (11) and thymol (111), p-cymene-2,3-diol (I; 2,3-dihydroxy-4-isopropyl-l-methylbenzene) was isolated for the first time from thyme. The structure of I was elucidated using 'H nuclear magnetic resonance (NMR), I3C NMR, and mass spectrometry. Antioxidative activity was investigated with the Rancimat method (100°C) and the Schaal test (60°C). Compound I exhibited the strongest antioxidative activity which was greater than that of a-tocopherol and butylated hydroxyanisole. Five thyme species were analysed by means of HPLC with electrochemical detection for the concentration of compounds 1-111. The highest amounts of 1-111 were found in Thymus uulgaris L.