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Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity

✍ Scribed by Zurich, Marie-Gabrielle; Stanzel, Sven; Kopp-Schneider, Annette; Prieto, Pilar; Honegger, Paul

Book ID
123059518
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
301 KB
Volume
27
Category
Article
ISSN
0887-2333

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The intravenous, short-acting general anesthetic propofol was applied to three-dimensional (aggregating) cell cultures of fetal rat telencephalon. Both the clinically used formulation (Disoprivan@, ICI Pharmaceuticals, Cheshire, England) and the pure form (2,6-diisopropylphenol) were tested at two d