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Evaluation of a new oil adjuvant for use in peptide-based cancer vaccination

โœ Scribed by Kanako Iseki; Hiromi Matsunaga; Nobukazu Komatsu; Shigetaka Suekane; Masanori Noguchi; Kyogo Itoh; Akira Yamada


Book ID
108586810
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
264 KB
Volume
101
Category
Article
ISSN
1347-9032

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โœ Weiguang Zeng; David C. Jackson; Keith Rose ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 554 KB

Synthetic lipopeptides are showing promise as vaccine candidates, but until now it has been very difficult to prepare them in homogeneous form. We describe the synthesis and characterization of a new water-soluble, four-branched template with a built-in lipophilic adjuvant (Pam3Cys). Through the use