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Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation

โœ Scribed by Paul J. Martin; Ji Pei; Ted Gooley; Claudio Anasetti; Frederick R. Appelbaum; Joachim Deeg; John A. Hansen; Richard A. Nash; Effie W. Petersdorf; Rainer Storb; Victor Ghetie; John Schindler; Ellen S. Vitetta


Book ID
116277860
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
172 KB
Volume
10
Category
Article
ISSN
1083-8791

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Selective depletion of marrow-T cytotoxi
โœ D. Maraninchi; C. Mawas; D. Guyotat; J. Reiffers; J. P. Vernant; N. Gratecos; J. ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 418 KB

In vitro depletion of mature pan-T lymphocytes has been widely and successfully used to prevent acute graft-versus-host disease (GVHD) after allogeneic bone-marrow transplantation (BMT). However, this procedure has been associated with a high incidence of graft failure and leukemic relapse. In this