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Evaluation of (4-aminobutyloxy)quinolines as a novel class of antifungal agents

✍ Scribed by Vandekerckhove, Stéphanie; Tran, Hai Giang; Desmet, Tom; D’hooghe, Matthias

Book ID
120664692
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
314 KB
Volume
23
Category
Article
ISSN
0960-894X

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✍ Kazutaka Nakamoto; Itaru Tsukada; Keigo Tanaka; Masayuki Matsukura; Toru Haneda; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 297 KB

Quinoline amide, azaindole amide and pyridine amides were synthesized and tested for in vitro antifungal activity against fungi. These synthesized amides have potent antifungal activity against Candida albicans and Aspergillus fumigatus. Our results suggest that hetero ring amides may be potent anti